SmartDrug

Nootropics

NootropicsPrimer

Notes on Nootropics with evidence

Key resources

• Nootropic article at Wikipedia
• Towards responsible use of cognitive-enhancing drugs by the healthy - commentary in Nature

  Studies on effectiveness of various Nootropics

• Nefiracetam [1]
• Bacopa monniera - [2]
• Cytidine (5′)-diphosphocholine - [3]
• Piracetam, aniracetam, meclofenoxate, fipexide - [4]

Other notes

Caffeine

• Caffeine - a users guide to getting optimally wired

Ginseng

• Page on Ginseng at healthyeatingclub.com - includes survey of scientific evidence

The information below is uncited - it would be good to collect links to specific studies to help assess which might be effective. ThufirHawat

Racetam Groups

<tablewidth="95%">Agent

Mechanism

Effect

Dosage

<tablewidth="95%">Piracetam

mechanism

effect

1600 mg - 9600 mg

<tablewidth="95%">Aniracetam

mechanism

effect

dosage

<tablewidth="95%">Oxyracetam

mechanism

effect

dosage

Inhibitors

<tablewidth="95%">Agent

Mechanism

Effect

Dosage

<tablewidth="95%">Huperzine A

Inhibits Acetylcholinesterase Increases Acetylcholine levels

effect

dosage

<tablewidth="95%">Vinpocetine

Inhibits Phospodiesterases Increases levels of cAMP, cGMP

effect

dosage

<tablewidth="95%">Galantamine

Inhibits Acetylcholinesterase Increases Acetylcholine levels

Effect

Dosage

<tablewidth="95%">L-Deprenyl

Inhibits MAO-B Increases Dopamine Levels

Effect

Dosage

<tablewidth="95%">Tolcapone

Inhibits COMT Increases Dopamine Levels Increases Epinephrine levels Increases Norepinephrine Levels

Effect

Dosage

<tablewidth="95%">2C-E

Inhibits MAO-B Increases Serotonin

Stimulant at low doses

Dose:5-10mg

Neuroreceptor Agents

<tablewidth="95%">Agent

Mechanism

Effect

Dosage

<tablewidth="95%">Hydergine

Stimulates dopaminergic and seratonergic receptors Inhibits Alpha Adrenoceptors Increases MAO levels

effect

dosage

Neurotransmitter Precursors

<tablewidth="95%">Agent

Mechanism

Effect

Dosage

<tablewidth="95%">5-HTP

Neurotransmitter precursor for Serotonin Increases serotonin levels

effect

dosage

<tablewidth="95%">DMAE

Neurotransmitter precursor for choline Increase Acetylcholine Levels

effect

dosage

<tablewidth="95%">Centrophenoxine

Neurotransmitter precursor for choline Increases acetylcholine levels Reduces Lipofuscins

effect

dosage

<tablewidth="95%">Acetyl-L-Carnitine

Neurotransmitter Precursor for Acetylcholine

Effect

Dosage

<tablewidth="95%">Alpha-GPC

Neurotransmitter Precursor for Choline

Effect

Dosage

<tablewidth="95%">Choline Citrate

Neurotransmitter Precursor for Acetylcholine

Effect

Dosage

<tablewidth="95%">Choline Bitartrate

Neurotransmitter Precursor for Acetylcholine

Effect

Dosage

<tablewidth="95%">Citicoline

Mechanism

Effect

Dosage

Stimulants

StimulantsPrimer?

<tablewidth="95%">Agent

Mechanism

Effect

Dosage

<tablewidth="95%">Caffeine

Mechanism

Effect

Dosage

<tablewidth="95%">Ritalin

Mechanism

Effect

Dosage

<tablewidth="95%">Adderal

Mechanism

Effect

Dosage

<tablewidth="95%">Modanifil

Mechanism

Effect

Dosage

<tablewidth="95%">Ephedra

Mechanism

Effect

Dosage

Essential Nutrition

NutrientsPrimer?

Amino Acids

Essential

<tablewidth="95%">Amino Acid

Function

Dosage

<tablewidth="95%">Isoleucine

Function

Dosage

<tablewidth="95%">Leucine

Function

Dosage

<tablewidth="95%">Lysine

Function

Dosage

<tablewidth="95%">Methionine

Function

Dosage

<tablewidth="95%">Phenylalanine

Function

Dosage

<tablewidth="95%">Threonine

Function

Dosage

<tablewidth="95%">Tryptophan

Function

Dosage

<tablewidth="95%">Valine

Function

Dosage

<tablewidth="95%">Arginine

Function

Dosage

<tablewidth="95%">Histidine

Function

Dosage

Nonessential

<tablewidth="95%">Amino Acid

Function

Dosage

<tablewidth="95%">Alanine

Function

Dosage

<tablewidth="95%">Asparagine

Function

Dosage

<tablewidth="95%">Aspartate

Function

Dosage

<tablewidth="95%">Cysteine

Function

Dosage

<tablewidth="95%">Glutamate

Function

Dosage

<tablewidth="95%">Glutamine

Function

Dosage

<tablewidth="95%">Glycine

Function

Dosage

<tablewidth="95%">Proline

Function

Dosage

<tablewidth="95%">Serine

Function

Dosage

<tablewidth="95%">Tyrosine

Function

Dosage

Nonstandard

<tablewidth="95%">Amino Acid

Function

Dosage

<tablewidth="95%">L-Dopa

Neurotransmitter Precursor for Dopamine Increases Dopamine Levels

Dosage

Essential Fatty Acids

Essential Vitamins

Pantothenic Acid(B-5)

Essential Minerals

Miscellaneous

<tablewidth="95%">Agent

Mechanism

Effect

Dosage

<tablewidth="95%">Ginko Biloba

Mechanism

Effect

Dosage

<tablewidth="95%">Ginseng

Mechanism

Effect

Dosage

<tablewidth="95%">Mucuna Pruriens

Mechanism

Effect

Dosage

<tablewidth="95%">Yohimbe

Mechanism

Effect

Dosage