Editing SmartDrug

== Nootropics == '''NootropicsPrimer''' [[BR]] == Notes on Nootropics with evidence == === Key resources === * [http://en.wikipedia.org/wiki/Nootropic Nootropic article at Wikipedia] * [https://en.wikipedia.org/wiki/Category:Nootropics List of Nootropics and Smart Drugs] * [http://trackmystack.com/stacks Stack Supplements for Synergy] * [http://www.braintropic.com The Complete Guide to Nootropics] * [http://www.nature.com/nature/journal/vaop/ncurrent/full/456702a.html Towards responsible use of cognitive-enhancing drugs by the healthy] - commentary in Nature * [http://www.brainprotips.com/best-nootropics Identifying the Best Nootropics] * [http://acimmune.com/content/resources/froestl_2014_part2.pdf Cognitive Enhancers (Nootropics). Part 2: Drugs Interacting with Enzymes] === Studies on effectiveness of various Nootropics === * Nefiracetam [http://www.ncbi.nlm.nih.gov/pubmed/10869513?dopt=Citation] * Bacopa monniera - [http://www.ncbi.nlm.nih.gov/pubmed/18683852?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum] * Cytidine (5′)-diphosphocholine - [http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=548494] * Piracetam, aniracetam, meclofenoxate, fipexide - [http://www.ncbi.nlm.nih.gov/pubmed/2854355?dopt=Citation] == Other notes == === Caffeine === * [http://scienceblogs.com/developingintelligence/2008/02/optimally_wired_a_caffeine_use.php Caffeine - a users guide to getting optimally wired] === Ginseng === * [http://www.healthyeatingclub.org/info/articles/diseases/ginseng.htm Page on Ginseng at healthyeatingclub.com] - includes survey of scientific evidence The information below is uncited - it would be good to collect links to specific studies to help assess which might be effective. ThufirHawat Citations are being added. * I advise reading them because I'm trying to include both supporting and detracting articles. Also, where info is sparse I include animal studies, and pathological studies - CassoX === Racetam Groups === |'''Agent'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|'''Citations'''| |'''Piracetam'''|mechanism|effect|1600 mg - 9600 mg|[http://jop.sagepub.com/content/4/4/219.short][http://www.ncbi.nlm.nih.gov/pubmed/10796585][http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0447.1976.tb00107.x/abstract][http://www.ncbi.nlm.nih.gov/pubmed/20877425][http://www.ncbi.nlm.nih.gov/pubmed/10338102][http://www.ncbi.nlm.nih.gov/pubmed/14624946]| |'''Aniracetam'''|mechanism|effect|750 mg - 1500 mg|[http://jop.sagepub.com/content/4/4/219.short][http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0N-475J8YF-2G5&_user=10&_coverDate=05%2F31%2F1985&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_searchStrId=1648669111&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=a63fe53d944db4939f83c9c63934342e&searchtype=a][http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0N-477XNGW-CV&_user=10&_coverDate=07%2F31%2F1987&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_searchStrId=1648667448&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=6000ee3b662f0924c00ceb46fc59d9fd&searchtype=a][http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0N-477XNGW-CV&_user=10&_coverDate=07%2F31%2F1987&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_searchStrId=1648667448&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=6000ee3b662f0924c00ceb46fc59d9fd&searchtype=a][http://www.braintropic.com/nootropics/aniracetam/]| |'''Oxiracetam'''|mechanism|effect|800mg - 1600mg|[http://content.karger.com/ProdukteDB/produkte.asp?Doi=118805][http://journals.lww.com/clinicalneuropharm/Abstract/1986/00093/Experimental_Behavioral_Studies_with_Oxiracetam_on.5.aspx][http://www.ncbi.nlm.nih.gov/pubmed/8456595][http://www.ncbi.nlm.nih.gov/pubmed/15922047][http://www.ncbi.nlm.nih.gov/pubmed/11099768][http://www.ncbi.nlm.nih.gov/pubmed?term=oxiracetam%20cognitive%20enhancer]| |'''Nefiracetam'''|mechanism|effect|dosage|[http://www.ncbi.nlm.nih.gov/pubmed/10869513?dopt=Citation]| |'''Pramiracetam'''|mechanism|effect|200 mg - 400 mg|[http://www.braintropic.com/nootropics/pramiracetam/]| |'''Phenylpiracetam'''|poorly characterized|antiamnesia, psychostimulatory effect|100-200mg|[http://www.brainprotips.com/phenylpiracetam/] [http://www.braintropic.com/nootropics/phenylpiracetam/]| [[BR]] [[BR]] === Inhibitors === |'''Agent'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|'''Citations'''| |'''Huperzine A'''|Inhibits Acetylcholinesterase[[BR]]Increases Acetylcholine levels|effect|50 mcg - 200 mcg|[http://www.braintropic.com/nootropics/huperzine-a/]| |'''Vinpocetine'''|Inhibits Phospodiesterases[[BR]]Increases levels of cAMP, cGMP|effect|5 mg - 10 mg|[http://www.braintropic.com/nootropics/vinpocetine/]| |'''Galantamine'''|Inhibits Acetylcholinesterase[[BR]]Increases Acetylcholine levels|Effect|Dosage|source| |'''L-Deprenyl'''|Inhibits MAO-B[[BR]]Increases Dopamine Levels|Effect|Dosage|source| |'''Tolcapone'''|Inhibits COMT[[BR]]Increases Dopamine Levels[[BR]]Increases Epinephrine levels[[BR]]Increases Norepinephrine Levels|Effect|Dosage|source| |'''2C-E'''|Inhibits MAO-B[[BR]]Increases Serotonin|Stimulant at low doses|Dose:5-10mg|source| [[BR]] [[BR]] === Neuroreceptor Agents === |'''Agent'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|'''Citations'''| |'''Hydergine'''|Stimulates dopaminergic and seratonergic receptors[[BR]]Inhibits Alpha Adrenoceptors[[BR]]Increases MAO levels|effect|dosage|source| [[BR]] [[BR]] === Neurotransmitter Precursors === |'''Agent'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|'''Citations'''| |'''5-HTP'''|Neurotransmitter precursor for Serotonin[[BR]]Increases serotonin levels|effect|dosage|source| |'''DMAE'''|Neurotransmitter precursor for choline[[BR]]Increase Acetylcholine Levels|effect|dosage|source| |'''Centrophenoxine'''|Neurotransmitter precursor for choline[[BR]]Increases acetylcholine levels[[BR]]Reduces Lipofuscins|effect|dosage|source| |'''Acetyl-L-Carnitine'''|Neurotransmitter Precursor for Acetylcholine|Effect|Dosage|source| |'''Alpha-GPC'''|Neurotransmitter Precursor for Choline|Effect|Dosage|source| |'''Choline Citrate'''|Neurotransmitter Precursor for Acetylcholine|Effect|Dosage|source| |'''Choline Bitartrate'''|Neurotransmitter Precursor for Acetylcholine|Effect|Dosage|source| |'''Citicoline'''|Mechanism|Effect|Dosage|source| [[BR]] [[BR]] == Stimulants == '''StimulantsPrimer'''[[BR]] |'''Agent'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|'''Citations'''| |'''Caffeine'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|source| |'''Ritalin'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|source| |'''Adderal'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|source| |'''Modanifil'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|[http://corpina.com/modafinil-feeling-tired-isnt-option/]| |'''Ephedra'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|source| [[BR]] [[BR]] == Essential Nutrition == '''NutrientsPrimer'''[[BR]] == Amino Acids == === Essential === |'''Amino Acid'''|'''Function'''|'''Dosage'''|'''Citations'''| |'''Isoleucine'''|Function|Dosage|source| |'''Leucine'''|Function|Dosage|source| |'''Lysine'''|Function|Dosage|source| |'''Methionine'''|Function|Dosage|source| |'''Phenylalanine'''|Function|Dosage|source| |'''Threonine'''|Function|Dosage|source| |'''Tryptophan'''|Function|Dosage|source| |'''Valine'''|Function|Dosage|source| |'''Arginine'''|Function|Dosage|source| |'''Histidine'''|Function|Dosage|source| === Nonessential === |'''Amino Acid'''|'''Function'''|'''Dosage'''|'''Citations'''| |'''Alanine'''|Function|Dosage|source| |'''Asparagine'''|Function|Dosage|source| |'''Aspartate'''|Function|Dosage|source| |'''Cysteine'''|Function|Dosage|source| |'''Glutamate'''|Function|Dosage|source| |'''Glutamine'''|Function|Dosage|source| |'''Glycine'''|Function|Dosage|source| |'''Proline'''|Function|Dosage|source| |'''Serine'''|Function|Dosage|source| |'''Tyrosine'''|Function|Dosage|source| === Nonstandard === |'''Amino Acid'''|'''Function'''|'''Dosage'''|'''Citations'''| |'''L-Dopa'''|Neurotransmitter Precursor for Dopamine[[BR]]Increases Dopamine Levels|Dosage|source| === Essential Fatty Acids === [[BR]] === Essential Vitamins === |'''Agent'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|'''Citations'''| |'''Pantothenic Acid'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|source| [[BR]] === Essential Minerals === [[BR]] == Miscellaneous == [[BR]] |'''Agent'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|'''Citations'''| |'''Ginko Biloba'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|source| |'''Ginseng'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|source| |'''Mucuna Pruriens'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|source| |'''Yohimbe'''|'''Mechanism'''|'''Effect'''|'''Dosage'''|source| [[BR]] [[BR]]

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